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331 Additionally, the matricellular protein SPARC, a novel tumor-derived vascular permeability factor, disrupts the endothelial barrier through vascular cell adhesion molecule 1 and p38 MAPK-mediated signaling, thereby promoting the metastatic competence of tumor cells

WHOLESALE

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The protein machinery of the ETC is composed of five enzyme complexes and two electron mobility carriers including the complex I (CI, NADH–ubiquinone oxidoreductase), complex II (CII, succinate dehydrogenase, SxDH), complex III (CIII, cytochrome bc1 oxidoreductase), complex IV (CIV, cytochrome c oxidase), ATP synthase, and the electron mobility carriers ubiquinone and cytochrome c (Qiu et al., 2018)